化合物 CCPA T21519

Product Introduction
Bioactivity


英文名: CCPA

描述: CCPA (2-chloro-N(6)cyclopentyladenosine) 是一种有效的选择性腺苷 A1 受体激动剂。

体外活性: CCPA suppressed the mRNA and protein expressions of CnAβ and exerted antihypertrophic effects to a greater degree than CsA. The inhibition of CCPA on cardiomyocyte hypertrophy was counteracted by the A1 receptor antagonist DPCPX[1].

体内活性: CCPA (CCPA) was synthesized as a potential high affinity ligand for A1 adenosine receptors. Binding of [3H]PIA to A1 receptors of rat brain membranes was inhibited by CCPA with a Ki-value of 0.4 nM, compared to a Ki-value of 0.8 nM for the parent compound N6-cyclopentyladenosine (CPA)[2].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 55 mg/ml (148.73 mM)


关键字: 2 Chloro N6 cyclopentyladenosine | 2-Chloro-N-6-cyclopentyladenosine | 2ChloroN6cyclopentyladenosine

相关产品: N6-(2-Phenylethyl)adenosine | Proxyphylline | 8-Cyclopentyl-1,3-dimethylxanthine | A3AR agonist 2 | CPI-444 | KFM19 | Xanthine amine congener trihydrochloride | AB928 | Derenofylline | Adenosine antagonist-1

相关库: Nucleotide Compound Library | Neurotransmitter Receptor Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Human Metabolite Library | Neuronal Signaling Compound Library | GPCR Compound Library | NO PAINS Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途