化合物VU0483605 T21747

Product Introduction
Bioactivity


英文名: VU0483605

描述: VU0483605 是一种有效的特异性 mGluR1 正变构调节剂，对人和大鼠的 EC50 分别为 390 和 356 nM。

体外活性: VU0483605 shows excellent mGlu1 PAM activity at both human and rat (pEC50 = 6.45 ± 0.11, 113 ± 5% Glu Max) and no activity as an mGlu4 PAM (EC50 >10 μM)[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 95 mg/mL (212.68 mM)


关键字: Inhibitor | inhibit | VU-0483605 | Metabotropic glutamate receptors | allosteric modulator | brain penetrant | metabotropic glutamate | VU 0483605 | VU0483605 | mGluR

相关产品: MNI 137 | Biphenylindanone A | GYKI 53655 hydrochloride | (1R,2S)-VU0155041 | Fenobam | pep2-EVKI acetate(1315378-67-6 free base) | DNQX | S-Sulfo-L-cysteine sodium salt | NBQX Disodium | HBT1

相关库: Anti-Neurodegenerative Disease Compound Library | Neurotransmitter Receptor Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途