化合物ML-097 T21970

Product Introduction
Bioactivity


英文名: ML-097

描述: ML-097 是 Ras 相关 GTP 酶的泛激活剂。

体外活性: Activators of Cdc42 function might have a beneficial function in solid tumors and ameliorate faciogenital dysplasia where Cdc42 GEF is mutant. Rho GTPases affect cell proliferation and migration (11). In some cases underexpression is associated with cancer[1].

体内活性: Rac2 is selectively expressed in immune cells and human Rac2 mutations result in immunodeficiency. Therefore, activators of Rac2 or other Rac family members might be of benefit in these diseases. Rac1 is important for maintaining hair follicle integrity and a rac1 deficiency in the skin causes nearly complete hair loss in an animal model[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 4 mg/mL(13.03mM)


关键字: Ras | Rac1 | CID-2160985 | cell division cycle 42 | ML 097 | ML097 | CID 2160985 | Inhibitor | CID2160985 | inhibit | Rab7 | ML-097

相关产品: Exo-1 | CCG-63802 | BQU57 | Compound C108 | QS11 | Dynamin inhibitory peptide Acetate | RBC10 | CCG 203769 | CCG-63808 | CCG-50014

相关库: Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | NO PAINS Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途