化合物NS3694 T22119
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
10 mg | 426834-38-0 | ¥1,160.00 | 询底价 |
1 mg | 426834-38-0 | ¥258.00 | 询底价 |
100 mg | 426834-38-0 | ¥5,120.00 | 询底价 |
50 mg | 426834-38-0 | ¥3,490.00 | 询底价 |
5 mg | 426834-38-0 | ¥655.00 | 询底价 |
500 mg | 426834-38-0 | ¥10,700.00 | 询底价 |
1 mL | 426834-38-0 | ¥719.00 | 询底价 |
2 mg | 426834-38-0 | ¥373.00 | 询底价 |
25 mg | 426834-38-0 | ¥2,390.00 | 询底价 |
Product Introduction
Bioactivity
英文名: NS3694
描述: NS3694 是一种凋亡抑制剂,可抑制凋亡小体形成和半胱天冬酶活化。
体外活性: NS3694 (10, 50, and 100 μM) specifically inhibits cytochrome c- and dATP-induced DEVDase activation and processing of caspases and caspase substrates, thus inhibiting the mitochondria-mediated apoptosis. NS3694 inhibits the formation of the apoptosome Apaf-1 by blocking the activation of the initiator caspase-9. In MCF-casp3 cells, NS3694 (10-100 μM) inhibits dose-dependently caspase 9, 3, and 7 processing, DFF45/ICAD, and PARP cleavage, and DEVDase activity and inhibits TNF-induced effector caspase activation and apoptosis[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 55 mg/mL (153.33 mM)
关键字: Inhibitor | NS-3694 | Apaf-1 | Apoptosis | inhibit | caspase-9 | NS 3694 | apoptosome inhibitor | NS3694 | cytochrome c
相关产品: Devimistat | Avadomide | Tubastatin A | PG-11047 2HCl | Flurochloridone | Doxorubicin hydrochloride | Sanguinarine chloride | Coenzyme Q9 | Madecassoside | LCS3
相关库: Bioactive Compounds Library Max | Inhibitor Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途