7-羟基-2-喹诺酮 T22226
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mL | 70500-72-0 | ¥259.00 | 询底价 |
500 mg | 70500-72-0 | ¥3,450.00 | 询底价 |
100 mg | 70500-72-0 | ¥1,430.00 | 询底价 |
10 mg | 70500-72-0 | ¥393.00 | 询底价 |
200 mg | 70500-72-0 | ¥2,130.00 | 询底价 |
50 mg | 70500-72-0 | ¥969.00 | 询底价 |
5 mg | 70500-72-0 | ¥278.00 | 询底价 |
25 mg | 70500-72-0 | ¥659.00 | 询底价 |
Product Introduction
Bioactivity
英文名: 7-Hydroxycarbostyril
描述: 7-Hydroxycarbostyril (3,4-Dihydro-7-hydroxycarbostyril) 是一种医药中间体。
体外活性: ?VPC-80051 as the first small molecule inhibitor of hnRNP A1 splicing activity discovered to date by using a computer-aided drug discovery approach. The inhibitor was developed to target the RNA-binding domain (RBD) of hnRNP A1. Further experimental evaluation demonstrated that VPC-80051 interacts directly with hnRNP A1 RBD and reduces AR-V7 messenger levels in 22Rv1 CRPC cell line. This study lays the groundwork for future structure-based development of more potent and selective small molecule inhibitors of hnRNP A1?RNA interactions aimed at altering the production of cancer-specific alternative splice isoforms[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 1mg/ml
关键字: 7 Hydroxycarbostyril | 7Hydroxycarbostyril | 7-Hydroxycarbostyril
相关库: Bioactive Compounds Library Max | NO PAINS Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途