苄基十二烷基二甲基氯化铵二水合物 T22269

Product Introduction
Bioactivity


英文名: Benzyldodecyldimethylammonium Chloride Dihydrate

描述: Benzyldodecyldimethylammonium chloride dihydrate 可以用作杀虫试剂，可以靶向耐药性细菌，如耐甲氧西林金黄色葡萄球菌、耐多药铜绿假单胞菌等，且具有浓度依赖性。

体外活性: Benzyldodecyldimethylammonium chloride dihydrate interacts strongly with cell surfaces in a concentration-dependent manner, and binds by ionic and hydrophobic interactions to microbial membrane surfaces, as manifested by phenomena such as membrane disruption and loss of membrane integrity with consequent leakage of essential intracellular constituents, which promote significant and irreversible changes in the cell structure[2]. Benzyldodecyldimethylammonium chloride dihydrate (0-40 mg/L; 0-24 hours) inhibits P. fluorescens with a MIC of 20 mg/L. At 5 mg/L, cells have the same growth behaviour as the control. At concentrations of 10 and 15 mg/L the growth profile is different from the control, and the cells start to grow only after 8 h of adaptation. At concentrations of ≥20 mg/L, BDMDAC inhibits cell growth[2].

体内活性: Benzyldodecyldimethylammonium chloride dihydrate (1-10 μM; 2 hours) results in a dose-dependent changes in the percent population of dead rat thymocyte cells[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 99 mg/mL (263.28 mM)


关键字: MRSA | inhibit | S. aureus | Benzyldodecyldimethylammonium Chloride Dihydrate | thymocyte | E. coli | Inhibitor | Disinfection,?QAC,?Biocide | Benzyldodecyldimethylammonium Chloride | Pseudomonas fluorescens | MDR | Bacterial | antimicrobial

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相关库: Antibiotics Library | Bioactive Compounds Library Max | Anti-Bacterial Compound Library | NO PAINS Compound Library | Anti-Infection Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途