化合物H-9 dihydrochloride T22833

Product Introduction
Bioactivity


英文名: H-9 dihydrochloride

描述: H-9 dihydrochloride 是一种具有有效性的蛋白激酶（ PKA）抑制剂。H-9 Dihydrochloride 在低浓度下显著降低 5-HT 的兴奋性反应。H-9 Dihydrochloride 会对咽部活动产生影响。H-9 Dihydrochloride 对 EGF (表皮生长因子)依赖的上皮细胞系的信号转导和细胞生长有抑制作用。

体外活性: Significantly inhibiting A431 cells, H-9 Dihydrochloride is more effective at inhibiting cyclic nucleotide-dependent protein kinases than other kinases[1].

体内活性: Microperfusing H-9 Dihydrochloride (100 μM) prevents picrotoxin seizures in 50% of the animals and significantly reduces the mean number of seizures and mean seizure duration[2].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : Soluble


关键字: H-9 | H9 Dihydrochloride | H 9 Dihydrochloride | H 9 | H-9 Dihydrochloride | H9 | H9 dihydrochloride | H 9 dihydrochloride

相关产品: Neratinib maleate | Endoxifen (Z-isomer) | (E)-AG 99 | PP2 | Theliatinib | Osimertinib | AG1557 | Lazertinib | EAI045 | Tyrphostin B44, (+) enantiomer

相关库: Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Kinase Inhibitor Library | Inhibitor Library | GPCR Compound Library | Bioactive Compound Library

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