化合物MCP110 T24437

Product Introduction
Bioactivity


英文名: MCP110

描述: MCP110 是 Ras 与 Raf-1 相互作用的抑制剂，可用于治疗人类肿瘤的研究。

体外活性: In A549 cells, MCP110 (20 μM) decreases Ras stimulation of Raf-1 and cyclin D level stimulated by the treatment with EGF (100 ng/mL), platelet-derived growth factor (20 ng/mL), and serum. In in HEK293 cells, MCP110 (10 and 20 μM) inhibits H-Ras (V12)-induced AP-1 activation. In fibrosarcoma HT1080 cells, MCP110 (1, 2, 5, 10, and 20 μM) shows a dose-dependent inhibition of elevated Raf-1 activity[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 245 mg/mL (481.67 mM)


关键字: astrocytomas | Inhibitor | Raf kinases | colorectal | cancer | inhibit | Raf-1 | Raf | Ras | MCP110

相关产品: RAF709 | Raf inhibitor 3 | Pluripotin | Regorafenib Hydrochloride | Sorafenib tosylate | Agerafenib | I-49 free base | L-779450 | Ro 5126766 | PROTAC BRAF-V600E degrader-1

相关库: Anti-Prostate Cancer Compound Library | Anti-Cancer Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Inhibitor Library | GPCR Compound Library | Anti-Colorectal Cancer Compound Library | Anti-Obesity Compound Library | PPI Inhibitor Library | Bioactive Compound Library

化合物MCP110 T24437信息由TargetMol中国为您提供，如您想了解更多关于化合物MCP110 T24437报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途