化合物Etarotene T25393

Product Introduction
Bioactivity


英文名: Etarotene

描述: Etarotene (Arotinoid ethyl sulphone) 是一种芦荟酸的乙基磺酰基衍生物，具有诱导分化和潜在的抗肿瘤活性。Etarotene 是一种胶原蛋白酶抑制剂，可用来研究银屑病。

体内活性: Ro 15-1570 (6 mg/kg; oral; 1 and 2 weeks; rats) show weight loss, alopecia, erythema, desquamation of the skin, and alterations of the skeletal system. The present demonstration that the arotinoid ethyl sulfone Ro 15-1570 was devoid of bone toxicity constitutes major progress in the pharmacologic development of retinoids with a better balance between therapeutic and adverse effects.[5]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: Etarotene

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途