化合物ASM-024 T26666
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
5 mg | 1609534-88-4 | ¥4,480.00 | 询底价 |
1 mL | 1609534-88-4 | ¥3,650.00 | 询底价 |
1 mg | 1609534-88-4 | ¥1,780.00 | 询底价 |
500 mg | 1609534-88-4 | ¥34,800.00 | 询底价 |
10 mg | 1609534-88-4 | ¥6,380.00 | 询底价 |
100 mg | 1609534-88-4 | ¥17,500.00 | 询底价 |
50 mg | 1609534-88-4 | ¥12,900.00 | 询底价 |
25 mg | 1609534-88-4 | ¥9,620.00 | 询底价 |
Product Introduction
Bioactivity
英文名: ASM-024
描述: ASM-024是一种有效的烟碱受体激动剂,是一种小分子合成哌嗪化合物,可促进β2-肾上腺素受体不同的靶点和信号通路介导平滑肌松弛,是治疗哮喘和慢性阻塞性支气管炎的潜在化合物,具有抗炎活性。
体外活性: Incubation of HBSMC cells with ASM-024 did not induce significant production of cAMP compared to salbutamol or formoterol treated cells.[1] Fifteen minutes of incubation of hBSMC with ASM-024 alone had no effect on [Ca2+]i. However, a 10 minute pre-treatment with ASM-024 decreased [Ca2+]i rise in cells challenged with 10-6 M histamine or methacholine.[1]
体内活性: ASM-024 increased in vitro relaxation response to maximally effective concentration of short—acting beta-2 agonists in dog and human bronchi.[1] ASM-024 induces smooth muscle relaxation of β2-AR desensitized tracheas.[1]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 2.34 mg/mL (10.01 mM)
关键字: ASM 024 | ASM-024 | ASM-024 cation | ASM024
相关产品: GNF-7 | Ribavirin | Propantheline bromide | α-Thujone | PHA 543613 | Tubotaiwine | Cyclodrine | Nitrobenzylthioinosine | Anisodamine Hydrobromide | S 24795
相关库: Anti-Neurodegenerative Disease Compound Library | Drug Repurposing Compound Library | Neurotransmitter Receptor Compound Library | Clinical Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途