加洛他滨 T27399

Product Introduction
Bioactivity


英文名: Galocitabine

描述: Galocitabine (Neofrutulon) 是一种胸苷酸合成酶抑制剂，可能用于治疗癌症。

体内活性: We performed 4-week toxicity studies of capecitabine (N(4)-pentyloxycarbonyl-5'-deoxy-5-fluorouridine), galocitabine (trimethoxybenzyl-5'-deoxy-5-fluorocytidine), 4 different fluoropyrimidine carbamate analogs. Four-week toxicity data for capecitabine in rats and mice were also obtained for comparison. Capecitabine, galocitabine, butyl, and isopentyl analogs showed similar toxicities in hematopoietic and intestinal organs at 1.0 mmol/kg. These compounds showed slight toxicity at 0.5 mmol/kg and no toxicity at 0.1 mmol/kg. [1]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 50 mg/mL (113.79 mM)


关键字: Galocitabine

相关库: Anti-Cancer Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途