化合物Minesapride T28043L

Product Introduction
Bioactivity


英文名: Minesapride

描述: Minesapride 是一种新型5-羟色胺4（5-HT4）受体部分激动剂，是一种潜在的胃肠道促动力剂，可用于治疗肠易激综合征伴便秘。

体内活性: Minesapride (1, 4, 12, or 40 mg; once daily; 4 weeks) improved in Minesapride 40 mg group abdominal symptoms score at week 4. In a phase 2 trial of patients with IBS-C in Japan, minesapride increased stool frequency (measured by CSBMs), reduced abdominal and overall IBS-C symptoms, and was well tolerated.[1]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 30 mg/mL (66.15 mM)


关键字: Minesapride | (S)4amino5chloroN((4((1(2hydroxyacetyl)piperidin4yl)methyl)morpholin2yl)methyl)2methoxybenzamide

相关产品: Tropisetron hydrochloride | (R)-Mirtazapine D3 | Metoclopramide | Escin IB | 5-HT2 agonist-1 | 5-HT2A&5-HT2C agonist-1 | Urapidil hydrochloride | Cilansetron | CP94253 hydrochloride | Granisetron

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途