根皮苷 T2922

Product Introduction
Bioactivity


英文名: Phlorizin

描述: Phlorizin (Phloridzin) 是非选择性的SGLT 抑制剂，也是Na+/K+-ATPase 抑制剂，对于hSGLT1和hSGLT2的Ki 值分别为 300 和 39 nM。

体内活性: 在糖尿病,肥胖症,以及应激性高血糖的治疗中,Phlorizin通过抑制位于近端肾小管和小肠粘膜的钠离子-葡萄糖协同转运子,产生肾脏糖尿并阻断肠道葡萄糖的吸收。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Ethanol : 43.6 mg/mL (100 mM)
DMSO : 60 mg/mL (137.49 mM)
H2O : < 1 mg/mL (insoluble or slightly soluble)


关键字: SGLT | Na+/K+ ATPase | Sodium potassium pump | Inhibitor | NSC-2833 | Phlorizin | inhibit | NSC2833 | Sodium-dependent glucose cotransporters

相关产品: Lasiodiplodin | Chalepensin | Paederosidic acid methyl ester | Ecdysone | PK095 | Odoroside H | Tirofiban hydrochloride monohydrate | Wilfordine | Sudoterb free base | BTB06584

相关库: Polyphenolic Natural Product Library | Mitochondria-Targeted Compound Library | Membrane Protein-targeted Compound Library | Saccharide and Glycoside Natural Product Library | Bioactive Compounds Library Max | GPCR Compound Library | Inhibitor Library | Traditional Chinese Medicine Monomer Library | Miao medicine Compound Library | Natural Product Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途