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其他生物化学试剂

齐墩果酸3-乙酸酯 T2S1396

英文名称:3-​O-​Acetyloleanolic acid
品牌 厂商性质 产地 货期
TargetMol 生产商 美国 现货

性能特点

生化试剂,可用于动物细胞实验

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产品参数
规格 CAS号 价格 操作
25 mg 4339-72-4 ¥1,790.00 询底价
10 mg 4339-72-4 ¥1,070.00 询底价
5 mg 4339-72-4 ¥689.00 询底价
100 mg 4339-72-4 ¥3,930.00 询底价
1 mg 4339-72-4 ¥289.00 询底价
50 mg 4339-72-4 ¥2,680.00 询底价
产品介绍

Product Introduction
Bioactivity


英文名: 3-​O-​Acetyloleanolic acid

描述: 3-​O-​Acetyloleanolic acid 是从 Vigna sinensisK. 种子中提取得到的一种齐墩果醇酸,可诱导癌细胞凋亡并拥有抗血管生成作用。

细胞实验: Modulation of phosphatidylserine externalization during apoptosis was measured using annexin V conjugated with the fluorescent dye fluorescein isothiocyanate (FITC). The HCT-116 cells were seeded onto 6-well plates at a density of 3*10^5 cells/well. After treatment with 25 uM 3-O-acetyloleanolic acid for 6 h, the cells were stained with the annexin V-FITC conjugate, and then imaged at a^40 objective magnification using a confocal laser scanning microscope.

体外活性: Expression of TRAIL-mediated apoptosis signaling-related death receptor DR5 was increased in 3-O-acetyloleanolic acid-treated HCT-116 cells. Activation of caspase-8 and caspase-3, critical mediators of extrinsic apoptosis signaling, was also increased by 3-O-acetyloleanolic acid. 3-O-acetyloleanolic acid induces apoptosis in HCT-116 cells mediated by an extrinsic apoptosis signaling cascade via up-regulation of DR5.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 2.5 mg/mL (5.01 mM)


关键字: Apoptosis | 3 ​O ​Acetyloleanolic acid | 3-O-Acetyloleanolic acid | Inhibitor | inhibit | 3​O​Acetyloleanolic acid

相关产品: LYN-1604 dihydrochloride | GSPT1 degrader-1 | Bendamustine | XST-14 | Valepotriate | Mocetinostat | Ubiquitin Isopeptidase Inhibitor I, G5 | NVP-TNKS656 | SGI-1027 | Thapsigargin

相关库: Anti-Tumor Natural Product Library | Terpene Natural Product Library | Selected Plant-Sourced Compound Library | Anti-Cancer Active Compound Library | Apoptosis Compound Library | Anti-COVID-19 Traditional Chinese Medicine Compound Library | Natural Product Library for HTS | Miao medicine Compound Library | NO PAINS Compound Library | Bioactive Compound Library

齐墩果酸3-乙酸酯 T2S1396信息由TargetMol中国为您提供,如您想了解更多关于齐墩果酸3-乙酸酯 T2S1396报价、型号、参数等信息,欢迎来电或留言咨询。

注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途

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