二氢环孢菌素A T31467
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mg | 59865-15-5 | ¥783.00 | 询底价 |
25 mg | 59865-15-5 | ¥4,630.00 | 询底价 |
10 mg | 59865-15-5 | ¥2,790.00 | 询底价 |
1 mL | 59865-15-5 | ¥4,810.00 | 询底价 |
50 mg | 59865-15-5 | ¥6,620.00 | 询底价 |
5 mg | 59865-15-5 | ¥1,930.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Dihydrocyclosporin A
描述: Dihydrocyclosporin A (Dihydrocyclosporin-A) 是 cyclosporin A 的密切相关的共同代谢物。它显着抑制前鞭毛体和细胞内无鞭毛体。
体外活性: Dihydrocyclosporin A was able to inhibit the proliferation of L. donovani promastigotes (IC50: 21.24 μM and 12.14 μM at 24 h and 48 h, respectively) and intracellular amastigotes (IC50: 5.23 μM and 4.84 μM at 24 and 48 h, respectively) in vitro. Dihydrocyclosporin A caused several alterations in the morphology and ultrastructure of L. donovani, especially in the mitochondria. However, Dihydrocyclosporin A showed high cytotoxicity towards cells of the mouse macrophage cell line RAW264.7, with CC50 values of 7.98 μM (24 h) and 6.65 μM (48 h).[2].
存储条件: store at low temperaturePowder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 60 mg/mL (49.81 mM)
关键字: Dihydrocyclosporin A
相关库: Natural Product Library for HTS | Microbial Natural Product Library | Natural Product Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途