二甲茚定 T31488

Product Introduction
Bioactivity


英文名: Dimethindene

描述: Dimethindene (Dimetindeno) 是 H1受体的选择性拮抗剂，阻断 K+电流。Dimethindene 表现出抗组胺和抗胆碱作用。

体外活性: In follicle-enclosed Xenopus oocytes, Dimethindene (5-500 μM) decreases Cromakalim cromakalim-induced K+ currents (IC50 = 29.5 μM)[1].

体内活性: In C57BL/6 mice with skin wound healing, Dimethindene (0.25 mg; i.p.) impairs cutaneous wound healing and delays skin wound closure[2].

存储条件: store at low temperaturePowder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: Dimethindene

相关产品: Hydroquinidine | 9-Hydroxycanthin-6-one | Lupanine | Dequalinium chloride | Azimilide Dihydrochloride | Nateglinide | NS3623 | Myomodulin acetate(110570-93-9 free base) | Kv2-IN-A1 | Loureirin B

相关库: Neurotransmitter Receptor Compound Library | FDA-Approved & Pharmacopeia Drug Library | GPCR Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途