化合物LJ-001 T32804

Product Introduction
Bioactivity


英文名: LJ-001

描述: LJ-001 显示出对几乎所有包膜 RNA 和 DNA 病毒的广谱活性。 LJ001 抑制传染性胃肠炎病毒 (TGEV) 和猪 delta 冠状病毒 (PDCoV) 的感染。

体外活性: In ST cells, LJ001 (12.5 µM) decreases the N-protein expression of TGEV and PDCoV and the gene mRNA expression in a time-dependent manner. LJ001 shows activities against HIV, HCV, influenza, Ebola, poxviruses and arenaviruses[3].

体内活性: In female BALB/c mice, oral gavage and intraperitoneal administration of LJ001 (20-50 mg/kg) shows no toxicity except a slight elevation in serum cholesterol levels[4].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 3.27 mg/mL (10 mM)


关键字: LJ-001

相关产品: HBF-0259 | Pirodavir | ERDRP-0519 | Alovudine | GS-9191 PM | Didemnin B | (R,1R)-Tenofovir amibufenamide | Antiviral agent 38 | Hypericin | 6'-O-Galloylsalidroside

相关库: Bioactive Compounds Library Max | Anti-Viral Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途