α常春藤皂甙 T3368
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mL | 27013-91-8 | ¥610.00 | 询底价 |
20 mg | 27013-91-8 | ¥760.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Alpha-Hederin
描述: Alpha-Hederin (Tauroside E) 是存在于黑种草种子中的一种单桥糖三萜皂苷,具有抗肿瘤作用。它可通过激活线粒体依赖性途径抑制胃癌细胞增殖,诱导凋亡,并有活性氧生成和谷胱甘肽减少。
激酶实验: For affinity determination, Nuciferine is subjected to primary radioligand binding assays tested at a single 10 μM concentration to displace 50% of the radioligand at a given receptor target. If a more than 50% of the radioligand is displaced, Nuciferine is selected for a secondary binding assay tested at 11 concentrations in triplicate in competition with the radioligand to generate an IC50 and Ki. Binding assays are performed in 96-well plates with 125 μL per well in appropriate binding buffer using radioligand at or near the Kd. Plates are incubated at room temperature in the dark for 90 min. Reactions are stopped by vacuum filtrations onto 0.3% polyethyleneimine soaked 96-well filter mats using a 96-well Filtermate harvester, followed by at least three washes of cold wash buffer. Scintillation cocktail is melted onto dried filters and radioactivity is counted using a Wallac Trilux Microbeta[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 55 mg/mL (73.24 mM)
关键字: a-Hederin | Apoptosis | Alpha Hederin | Inhibitor | alpha-Hederin | Alpha-Hederin | AlphaHederin | inhibit
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途