化合物Ro 67-7476 T3478

Product Introduction
Bioactivity


英文名: Ro 67-7476

描述: Ro 67-7476 是mGluR1的正变位调节剂，能增强表达 rat mGluR1a 的 HEK293 细胞中谷氨酸诱导的钙释放，EC50为 60.1 nM。它是 P-ERK1/2 激动剂，可以在外源添加谷氨酸的情况下激活 ERK1/2 磷酸化 (EC50=163.3 nM)。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 50 mg/mL (156.55 mM)


关键字: excitatory postsynaptic potentials | cAMP accumulation | mGluR | Ro 67-7476 | neuronal culture | Metabotropic glutamate receptors | Ro 67 7476 | inhibit | Ro 677476 | traumatic injury | mGluR1 | Inhibitor

相关产品: VU0422288 | CFMTI | VU 0469650 | DMeOB | VU0361737 | ADX88178 | CX614 | Licostinel | JNJ-46281222 | AZD-8529 mesylate

相关库: Anti-Neurodegenerative Disease Compound Library | Neurotransmitter Receptor Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Neuronal Signaling Compound Library | Target-Focused Phenotypic Screening Library | NO PAINS Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途