(±)14(15)-EET-SI T35464
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 μg | 218461-97-3 | ¥1,410.00 | 询底价 |
100 μg | 218461-97-3 | ¥4,900.00 | 询底价 |
50 μg | 218461-97-3 | ¥2,660.00 | 询底价 |
Product Introduction
Bioactivity
英文名: (±)14(15)-EET-SI
描述: Arachidonic acid is metabolized in the vascular endothelium to epoxytrienoic acids (EETs or EpETrEs) by cytochrome P450 enzymes. The EETs are released in response to acetylcholine, bradykinin, arachidonic acid, or cyclic stretch. (±)14(15)-EET-SI is the methyl sulfonamide analog of 14(15)-EET. This substitution results in a metabolically more stable compound because it is not sensitive to β-oxidation or membrane esterification. (±)14(15)-EET-SI is equipotent to 14(15)-EET in vascular agonist activity as measured by relaxation of precontracted bovine coronary arteries. In addition, 14(15)-EET and the methyl sulfonamide analog both stimulate tyrosine phosphorylation and induce mitogenesis in renal epithelial cells.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 10 mg/mL
Ethanol:PBS (pH 7.2) (1:2) : 0.3 mg/mL
Ethanol : 10 mg/mL
DMF : 10 mg/mL
关键字: (±)14(15)EETSI | (±)14(15) EET SI | 14(15)-EET-SI
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途