Tpl2 Kinase Inhibitor (hydrochloride) T35536
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | 价格 | 操作 |
---|---|---|
1 mg | ¥997.00 | 询底价 |
25 mg | ¥11,900.00 | 询底价 |
5 mg | ¥3,850.00 | 询底价 |
10 mg | ¥5,280.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Tpl2 Kinase Inhibitor (hydrochloride)
描述: Tpl2 kinase inhibitor is an inhibitor of tumor progression locus 2 (Tpl2; IC50= 0.05 μM).1It is selective for Tpl2 over MEK, p38 MAPK, Src, MK2, and PKC (IC50s = >40, 180, >400, 110, and >400 μM, respectively). Tpl2 kinase inhibitor inhibits LPS-induced TNF-α production in isolated human monocytes and whole blood (IC50s = 0.7 and 8.5 μM, respectively). It enhances differentiation induced by calcitriol in HL-60 and U937 leukemia cells when used at a concentration of 5 μM.2Tpl2 kinase inhibitor (5 μM) inhibits the proliferation of KG-1a leukemia cells.3
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMF : Slightly soluble
DMSO : Slightly soluble
关键字: Tpl-2 Kinase Inhibitor (hydrochloride) | Tpl2 Kinase Inhibitor (hydrochloride) | Tpl2 Kinase Inhibitor
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