BIX01294 (hydrochloride hydrate) T35567
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
10 mg | 1808255-64-2 | ¥2,950.00 | 询底价 |
1 mg | 1808255-64-2 | ¥525.00 | 询底价 |
50 mg | 1808255-64-2 | ¥9,760.00 | 询底价 |
5 mg | 1808255-64-2 | ¥1,970.00 | 询底价 |
Product Introduction
Bioactivity
英文名: BIX01294 (hydrochloride hydrate)
描述: The methylation of lysine residues on histones plays a central role in determining euchromatin structure and gene expression. The histone methyltransferase (HMTase) G9a can mono- or dimethylate lysine 9 on histone 3 (H3), contributing to early embryogenesis, genomic imprinting, and lymphocyte development. BIX01294 (hydrochloride hydrate) is a selective inhibitor of G9a HMTase (IC50 = 1.7 μM). It less effectively inhibits the HMTase G9a-like protein (GLP; IC50 = 38 μM) and has no effect on other known HMTases. BIX01294 has been used in combination with the calcium channel activator BayK8644 to facilitate the generation of induced pluripotent stem cells from somatic cells in vitro.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: H2O : 10 mg/mL
DMSO : 5 mg/mL
关键字: BIX01294 (hydrochloride hydrate) | hydrochloride Hydrate | BIX01294 | BIX 01294 | BIX-01294 (hydrochloride hydrate) | BIX-01294
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途