磷酸吡哆醛 T3578

Product Introduction
Bioactivity


英文名: Pyridoxal phosphate

描述: Pyridoxal phosphate (Vitamin B6 phosphate) 是维生素 B6 的活性形式，可抑制逆转录酶活性，用于研究迟发性运动障碍症。

体外活性: Pyridoxal phosphate results in an immediate reduction in the rate of DNA synthesis. Pyridoxal 5′-phosphate severely inhibits the DNA Polymerase and RNase H. Conjugation to pyridoxal phosphate fully inhibits NEIL2. Pyridoxal phosphate-conjugated NEIL2 shows much lower activity than the intact enzyme over a wide range of enzyme/substrate ratios. After Pyridoxal phosphate conjugation, the ability of NEIL2 to bind the THF-ligand is completely lost.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 50 mg/mL (202.31 mM)
H2O : 20.23mM


关键字: Pyridoxal | Pyridoxal phosphate | Pyridoxyl | Reverse Transcriptase | inhibit | Vitamin B6 Phosphate | Pyridoxyl Phosphate | Inhibitor | Pyridoxal Phosphate | Endogenous Metabolite

相关产品: Corilagin | Stavudine | RO-0335 | R-10015 | Zidovudine | Adefovir dipivoxil | Nevirapine | Efavirenz | Emtricitabine triphosphate tetrasodium salt | Abacavir sulfate

相关库: Anti-Aging Compound Library | Human Endogenous Metabolite Library | Drug Repurposing Compound Library | Approved Drug Library | Inhibitor Library | Natural Product Library for HTS | Preclinical Compound Library | NO PAINS Compound Library | Anti-infective Natural Product Library | Anti-Infection Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途