YW3-56 (hydrochloride) (technical grade) T36108

Product Introduction
Bioactivity


英文名: YW3-56 (hydrochloride) (technical grade)

描述: YW3-56 is an inhibitor of protein arginine deiminase 2 (PAD2) and PAD4 (IC50s = 0.5-1 and 1-5 μM, respectively).1It inhibits the growth of U2OS osteosarcoma cells (IC50= ~2.5 μM) in a p53-dependent mannerviainduction of SESN2 and subsequent inhibition of mTORC1. YW3-56 (10 mg/kg) reduces tumor growth in an S-180 murine sarcoma tumor model. It also inhibits tumor growth in the 1883 MDA-MB-231 breast cancer bone metastasis mouse xenograft model.2

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Methanol : 10 mg/mL


关键字: YW3 56 (hydrochloride) (technical grade) | YW356 (hydrochloride) (technical grade) | technical grade | YW3-56 (hydrochloride) | YW-3-56 (hydrochloride) (technical grade)

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途