盐酸CP-640186 T3622
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
2 mg | 591778-70-0 | ¥453.00 | 询底价 |
1 mg | 591778-70-0 | ¥315.00 | 询底价 |
5 mg | 591778-70-0 | ¥747.00 | 询底价 |
50 mg | 591778-70-0 | ¥3,950.00 | 询底价 |
25 mg | 591778-70-0 | ¥2,490.00 | 询底价 |
10 mg | 591778-70-0 | ¥1,190.00 | 询底价 |
100 mg | 591778-70-0 | ¥5,630.00 | 询底价 |
1 mL | 591778-70-0 | ¥858.00 | 询底价 |
Product Introduction
Bioactivity
英文名: CP-640186 hydrochloride
描述: CP-640186 hydrochloride (CP 640186 HCl) 是膜渗透性的乙酰辅酶A 羧化酶(ACC)抑制剂,抑制大鼠肝脏ACC1和大鼠骨骼肌ACC2的IC50为53 nM 和61 nM。
激酶实验: Aconitase activities are determined by homogenization of mouse brain tissues on ice at 10% w/v in CellLytic MT Mammalian Tissue Lysis/Extraction buffer, followed by centrifugation at 800×g?for 10?min at 4°C. Tissue lysates (50?μL) are then added to 200?μL of substrate mix (50?mM Tris/HCl pH 7.4, 0.4?mM NADP, 5?mM Na citrate, 0.6?mM MgCl2, 0.1% (v/v) Triton X-100 and 1U isocitrate dehydrogenase) and the reactions are incubated at 37°C for 15?min, followed by spectrophotometric absorbance measurements every minute for 15?min at 340?nm 37°C to determine the reaction slope. Aconitase activities of mouse brain tissues are then normalized to citrate synthase activities, which are determined using a citrate synthase assay kit.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 50 mg/mL (95.77 mM)
关键字: ACC, Acetyl Coenzyme A Carboxylase | CP 640186 | muscle fatty acid oxidation | CP 640186 Hydrochloride | CP640186 hydrochloride | C2C12 | HepG2 | H460 | CP640186 | human fibroblasts | inhibit | CP-640186 Hydrochloride | CP640186 Hydrochloride | Acetyl-CoA Carboxylase | muscle strips | CP-640186 | Inhibitor | CP 640186 hydrochloride
相关产品: ND-646 | PF-05175157 | Olumacostat Glasaretil | Moiramide B | TOFA | CMS-121 | Tralkoxydim | Quizalofop-P | Firsocostat | CP-640186
相关库: Anti-Hypertension Compound Library | Anti-Metabolism Disease Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Anti-Obesity Compound Library | Lipid Metabolism Compound Library | Metabolism Compound Library | NO PAINS Compound Library | Anti-Cardiovascular Disease Compound Library | Bioactive Compound Library
盐酸CP-640186 T3622信息由TargetMol中国为您提供,如您想了解更多关于盐酸CP-640186 T3622报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途