6α-Prostaglandin I1 T36238

Product Introduction
Bioactivity


英文名: 6α-Prostaglandin I1

描述: 6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions. 6α-PGI1 promotes cyclic AMP accumulation in human thyroid slices and cells in a concentration dependent manner. However, it is about 10-fold less potent than the β-isomer and 100-fold less potent than PGI2 in eliciting the response. 6α-PGI1 exhibits an IC50 of 350 ng/ml for inhibition of ADP-induced platelet aggregation, which is nearly 900-fold higher than that observed for PGI2 (0.4 ng/ml).

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : >5 (from 6b-PGI1)
Ethanol : >20 mg/mL (from 6b-PGI1)
DMF : >10 (from 6b-PGI1)
PBS (pH 7.2) : >80 μg (from 6b-PGI1)


关键字: 6α Prostaglandin I1 | 6αProstaglandin I1 | 6alpha-Prostaglandin I1 | 6a-Prostaglandin I1 | 6α-Prostaglandin I-1

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途