4-Methylumbelliferyl-α-L-Iduronide (free acid) T36370
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
500 μg | 66966-09-4 | ¥1,080.00 | 询底价 |
1 mg | 66966-09-4 | ¥1,690.00 | 询底价 |
5 mg | 66966-09-4 | ¥5,230.00 | 询底价 |
Product Introduction
Bioactivity
英文名: 4-Methylumbelliferyl-α-L-Iduronide (free acid)
描述: 4-Methylumbelliferyl-α-L-iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase, an enzyme found in cell lysosomes that is involved in the degradation of glycosaminoglycans such as dermatan sulfate and heparin sulfate. 4-Methylumbelliferyl-α-L-iduronide is cleaved by α-L-iduronidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. This substrate is used in assays that measure the activity of α-L-iduronidase, which is commonly deficient in a type of lysosomal storage disease called mucopolysaccharidosis.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: Ethanol : 2 mg/mL
DMSO : 5 mg/mL
DMF : 20 mg/mL
PBS (pH 7.2) : 2 mg/mL
关键字: 4MethylumbelliferylαLIduronide (free acid) | 4 Methylumbelliferyl α L Iduronide (free acid) | 4-Methylumbelliferyl-alpha-L-Iduronide | 4-Methylumbelliferyl-a-L-Iduronide | free acid | 4-Methylumbelliferyl-α-L-Iduronide
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