化合物Evixapodlin T36487
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 2374856-75-2 | ¥9,870.00 | 询底价 |
1 mL | 2374856-75-2 | ¥3,580.00 | 询底价 |
5 mg | 2374856-75-2 | ¥2,530.00 | 询底价 |
100 mg | 2374856-75-2 | ¥13,800.00 | 询底价 |
25 mg | 2374856-75-2 | ¥7,630.00 | 询底价 |
10 mg | 2374856-75-2 | ¥3,960.00 | 询底价 |
1 mg | 2374856-75-2 | ¥987.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Evixapodlin
描述: Evixapodlin (PD-1/PD-L1-IN 7) 是一种人 PD-1/PD-L1蛋白/蛋白相互作用抑制剂(IC50:0.213)。Evixapodlin 具有抗癌和抗病毒活性。
体外活性: Evixapodlin exhibits an ability to increase the production of IFN-γ and Granzyme B in both CD8+ and CD4+ T cells in individuals with chronic hepatitis B (CHB). Additionally, Evixapodlin enhances the frequency of Granzyme B-positive cells among HBV-specific CD8+ and CD4+ T cells.[1]
体内活性: Evixapodlin (10-50 mg/kg; intraperitoneal injection, daily, for 6 days) treatment results in over 90% occupancy of the PD-L1 target on tumor cells. Evixapodlin effectively suppresses tumor growth in a mouse colorectal tumor model (MC38) that expresses human PD-L1.[1]
存储条件: store at low temperature,keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 45.0 mg/mL (65.1 mM)
关键字: Evixapodlin | GS4224 | GS 4224
相关产品: H-Lys-Trp-Lys-OH acetate | Paederoside | Cephalotaxine | Compound TN1582(SC) | Mbx2329 | DDG-39 | Angelicin | Isomangiferin | ISOPIMPINELLIN | Tizoxanide
相关库: Drug Repurposing Compound Library | Anti-Cancer Compound Library | Anti-Cancer Drug Library | Immuno-Oncology Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Anti-Cancer Clinical Compound Library | Inhibitor Library | Anti-Cancer Active Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途