Lysine-specific Demethylase Inhibitor (1C) (hydrochloride) T36627
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
5 mg | 1234494-75-7 | ¥1,314.00 | 询底价 |
10 mg | 1234494-75-7 | ¥2,171.00 | 询底价 |
1 mg | 1234494-75-7 | ¥457.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Lysine-specific Demethylase Inhibitor (1C) (hydrochloride)
描述: Lysine-specific demethylase inhibitor (1C) (LSD inhibitor (1C)) is an inhibitor of LSD1, a repressive demethylase selective for histone H3 lysine 4 (H3K4).1,2LSD inhibitor (1C) inhibits LSD1 activity by 85.9% when used at a concentration of 10 μM.1It increases the level of H3K4 methylation, including H3K4me1 and H3K4me2 but not H3K9me2 levels, in HCT116 human colon carcinoma cells.2LSD inhibitor (1C) also induces re-expression of the Wnt signaling pathway proteins secreted frizzle-related protein 1 (SFRP1), SFRP4, and SFRP5, as well as the transcription factor GATA5, which are aberrantly silenced in HCT116 cells.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : Soluble
H2O : 50 mg/mL
关键字: Lysine-specific Demethylase Inhibitor (1C) | Lysinespecific Demethylase Inhibitor (1C) (hydrochloride) | Lysine specific Demethylase Inhibitor (1C) (hydrochloride)
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途