Deltorphin II (trifluoroacetate salt) T36722

Product Introduction
Bioactivity


英文名: Deltorphin II (trifluoroacetate salt)

描述: Deltorphin II is a peptide agonist of δ2-opioid receptors.1,2It is selective for δ-opioid receptors over μ- and κ-opioid receptors in radioligand bindings assays (Kis = 0.0033, >1, and >1 μM, respectively) and induces [35S]GTPγS binding in mouse brain membrane preparations (EC50= 0.034 μM). Deltorphin II (0.12 mg/kg) decreases the infarction zone:risk zone ratio in a rat model of myocardial ischemia-reperfusion injury induced by coronary occlusion, an effect that can be reversed by the δ2-opioid receptor antagonist naltriben but not the δ1-opioid receptor antagonist BNTX.3Intrathecal administration of deltorphin II (15 μg/animal) increases latency to withdraw in the paw pressure and tail-flick tests in rats.4

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMF:PBS (pH 7.2) (1:5) : 0.16 mg/mL
DMF : 15 mg/mL
DMSO : 1 mg/mL
Ethanol : Slightly soluble


关键字: Deltorphin II | Deltorphin II (trifluoroacetate salt)

Deltorphin II (trifluoroacetate salt) T36722信息由TargetMol中国为您提供，如您想了解更多关于Deltorphin II (trifluoroacetate salt) T36722报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途