(R)-Omeprazole (sodium salt) T36840

Product Introduction
Bioactivity


英文名: (R)-Omeprazole (sodium salt)

描述: (R)-Omeprazole is the inactive isomer of omeprazole , a gastric proton-pump inhibitor. A stereoselective hydroxylation of (R)-omeprazole is mediated primarily by cytochrome P450 (CYP) 2C19, whereas CYP3A4 favors sulfoxidation of the active (S)-enantiomer . (R)-Omeprazole has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of CYP2C19 in pooled human liver microsomes (IC50 = 8.1 μM).

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Ethanol : 1 mg/mL
DMSO : 5 mg/mL
PBS (pH 7.2) : 5 mg/mL
DMF : 5 mg/mL


关键字: (R) Omeprazole (sodium salt) | (R)Omeprazole (sodium salt) | Omeprazole

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途