Isogarcinol T36845
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 71117-97-0 | ¥11,900.00 | 询底价 |
10 mg | 71117-97-0 | ¥5,460.00 | 询底价 |
1 mg | 71117-97-0 | ¥686.00 | 询底价 |
5 mg | 71117-97-0 | ¥2,970.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Isogarcinol
描述: Isogarcinol is a natural polyisoprenylated benzophenone first isolated from plant species in the genus Garcinia. It has immunosuppressant actions, inhibiting the protein phosphatase calcineurin (IC50 = 36 μM) and suppressing the proliferation of T cells. Oral administration of isogarcinol in mice decreases delayed type hypersensitivity, prolongs graft survival in allogeneic skin transplants, suppresses inflammation in collagen-induced arthritis, and reduces clinical symptoms in experimental autoimmune encephalomyelitis. Isogarcinol inhibits the proliferation of HL-60 and PC-3 cancer cells (IC50s = 4 and 8 μg/ml, respectively) through cell cycle arrest and apoptosis.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMF : 25 mg/mL
Ethanol : 20 mg/mL
DMSO:PBS (pH 7.2) (1:10) : 0.1 mg/mL
DMSO : 25 mg/mL
关键字: Isogarcinol
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途