Pramlintide (acetate hydrate) T36911
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 196078-30-5 | ¥19,000.00 | 询底价 |
10 mg | 196078-30-5 | ¥7,870.00 | 询底价 |
5 mg | 196078-30-5 | ¥4,230.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Pramlintide (acetate hydrate)
描述: Pramlintide is a non-amyloidogenic analog of the antidiabetic peptide hormone amylin that contains proline residues substituted at positions 25, 28, and 29. It stimulates cAMP production in HEK293 cells expressing human amylin receptor 1a (AMY1a), AMY2a, and AMY3a (EC50s = 0.35, 22.9, and 0.89 nM, respectively). Pramlintide inhibits human islet amyloid polypeptide fibrilization in a concentration-dependent manner.
体内活性: In vivo, pramlintide (200 pg/kg) reduces brain levels of amyloid-β (1-40) and increases spontaneous alternation in the Y-maze in the Tg2576 transgenic mouse model of Alzheimer's disease.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 10 mg/mL
PBS (pH 7.2) : 5 mg/mL
关键字: Pramlintide (acetate hydrate) | acetate Hydrate | Pramlintide
Pramlintide (acetate hydrate) T36911信息由TargetMol中国为您提供,如您想了解更多关于Pramlintide (acetate hydrate) T36911报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途