PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) T37028

Product Introduction
Bioactivity


英文名: PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)

描述: The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3-binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: CHCl3:CH3OH:H2O (2.5:3:1) : 3.8 mg/mL
PBS (pH 7.2) : 10 mg/mL


关键字: PtdIns (3,4,5) P3 (1,2 dipalmitoyl) (sodium salt) | PtdIns(3,4,5)P3 (1,2dipalmitoyl) (sodium salt) | PtdIns-(3,4,5)-P-3 (1,2-dipalmitoyl) (sodium salt) | PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl)

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