D-erythro-MAPP T37056
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mg | 143492-38-0 | ¥315.00 | 询底价 |
500 μg | 143492-38-0 | ¥192.00 | 询底价 |
10 mg | 143492-38-0 | ¥2,100.00 | 询底价 |
5 mg | 143492-38-0 | ¥1,220.00 | 询底价 |
Product Introduction
Bioactivity
英文名: D-erythro-MAPP
描述: D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 μM; IC50 = 1-5 μM). It is selective for alkaline ceramidase over acid ceramidase (IC50 = >500 μM) as well as the serine/threonine protein phosphatase CAPP at concentrations up to 10 μM. D-erythro-MAPP increases intracellular ceramide levels, induces cell cycle arrest at the G0/G1 phase, and inhibits growth of HL-60 promyelocytic leukemia cells in a time- and concentration-dependent manner.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 0.1 mg/mL
Ethanol : 20 mg/mL
DMF : 20 mg/mL
Ethanol:PBS (pH 7.2) (1:2) : 0.5 mg/mL
关键字: D erythro MAPP | D-erythro-MAPP | DerythroMAPP
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途