2-Methylthio-AMP diTEA T37525
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 1227193-98-7 | ¥10,600.00 | 询底价 |
50 mg | 1227193-98-7 | ¥13,800.00 | 询底价 |
100 mg | 1227193-98-7 | ¥17,500.00 | 询底价 |
Product Introduction
Bioactivity
英文名: 2-Methylthio-AMP diTEA
描述: 2-Methylthio-AMP diTEA (2-MeSAMP) is a selective and direct antagonist of the P2Y12 receptor, effectively inhibiting ADP-dependent platelet aggregation[1][2][3].
体外活性: 2-Methylthio-AMP (2-MeSAMP) diTEA inhibits agonist-mediated αIIbβ3 activation in platelets[1]. 2-methylthio-AMP (50 μM; for 5 minutes) diTEA does not significantly inhibit thrombin, PAR1-AP, PAR4-AP, or ADP-mediated platelet Ca2+ mobilization. 2-methylthio-AMP diTEA fails to inhibit Ca2+ mobilization in P2Y12-deficient mouse platelets and does not raise cAMP or induce vasodilator-stimulated phosphoprotein phosphorylation in wild-type platelets[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: 2MethylthioAMP diTEA | 2 Methylthio AMP diTEA | 2-Methylthio-AMP diTEA
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途