3-羟基犬尿氨酸 T37683

Product Introduction
Bioactivity


英文名: 3-Hydroxykynurenine

描述: 3-Hydroxykynurenine (3-hydroxy-DL-Kynurenine) 是色氨酸的活性代谢物，可抑制酵母和大鼠肝脏醛脱氢酶 97% 和 69%。

体外活性: In CD3/CD28 bead-stimulated CD4+ T cells, 3-Hydroxykynurenine (0-100 μM) dose-dependently inhibits CD4+ T-cell proliferation (IC50 = 70 μM). 3-Hydroxykynurenine (0-100 μM) dose-dependently induces significant CD4+ T-cell-mediated cell[3].

体内活性: In BALB/c (H2d) mice, 3-Hydroxykynurenine (560 mg/kg; i.p.) significantly prolongs graft survival whether administered between days 1 to 7, days 7 to 14, or days 1 to 14[3].

存储条件: keep away from moisture,keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 1.4 mg/mL (6 mM)
Ethanol : 2 mg/mL
DMF : 0.5 mg/mL
PBS (pH 7.2) : 0.5 mg/mL


关键字: 3-Hydroxykynurenine

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途