Faropenem T38458
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 106560-14-9 | ¥10,600.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Faropenem
描述: Faropenem, a highly efficacious and orally bioavailable beta-lactam antibiotic, exhibits an extensive range of in vitro antimicrobial activity against diverse gram-positive and -negative aerobes and anaerobes. Notably, Faropenem possesses inherent resistance to hydrolysis by virtually all beta-lactamases, including extended-spectrum beta-lactamases and AmpC beta-lactamases. Moreover, Faropenem has been developed as an oral prodrug, namely faropenem medoxomil, for the investigation of respiratory tract infections.
体外活性: Faropenem is not active against methicillin-resistant Staphylococcus aureus , vancomycin-resistant Enterococcus faecium , Pseudomonas aeruginosa or Stenotrophomonas maltophilia[1].Faropenem is against all isolates?of B. anthracis .?The MIC values ranged from ≤0.06 to >64 μg/liter, and the MIC 90 value is 0.5 μg/ml. The MIC 90 value for Faropenem is lower than that observed for other β-lactams, such as Meropenem, Amoxicillin-clavulanate, and Penicillin, for which the MIC 90 values are 4 μg/ml, 4 μg/ml, and 8 μg/ml, respectively[2].
体内活性: Faropenem ( i.p. at 24 h postchallenge at 4-, 6-, and 12-h intervals; 10, 20, 40, and 80 mg/kg/day; 14 days) demonstrates a high level of activity against B. anthracis in the murine post-exposure prophylaxis inhalation model[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: Faropenem
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途