化合物LP-922056 T38776
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
2 mg | 1365060-22-5 | ¥298.00 | 询底价 |
1 mL | 1365060-22-5 | ¥589.00 | 询底价 |
10 mg | 1365060-22-5 | ¥787.00 | 询底价 |
25 mg | 1365060-22-5 | ¥1,490.00 | 询底价 |
1 mg | 1365060-22-5 | ¥197.00 | 询底价 |
50 mg | 1365060-22-5 | ¥2,380.00 | 询底价 |
100 mg | 1365060-22-5 | ¥3,980.00 | 询底价 |
5 mg | 1365060-22-5 | ¥538.00 | 询底价 |
Product Introduction
Bioactivity
英文名: LP-922056
描述: LP-922056 是 Notum Pectinacetylesterase 的抑制剂,对人和小鼠的 EC50 值分别为 21 nM 和 55 nM。
体外活性: LP-922056可作为一种补充化学工具,用于探索Notum在Wnt信号传导中的作用[2]。
体内活性: In mice, LP-922056 (3, 10, 30 mg/kg; gavage) significantly increases midshaft femur cortical bone thickness. LP-922056 (10 mg/kg) achieved high Cmax of 129 μM and AUC of 1533 μM•h while volume of distribution is 0.13 L/kg and low clearance is 0.49 mL/min•kg[1]. LP-922056 (10 mg/kg; oral) increases cortical bone thickness and strength in the midshaft femur, bone mass in the femoral neck, and vertebral body cortical shell[2].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 120 mg/mL (398.96 mM)
关键字: cortical | Pectinacetylesterase | thickness | orally | femur | inhibit | Wnt | lipase | bone | LP 922056 | Notum | Inhibitor | midshaft | LP-922056 | LP922056
相关产品: exo-IWR-1 | C-82 | JW74 | FzM1 | KYA1797K | FzM1.8 | SRI 37892 | Specnuezhenide | Cardiogenol C hydrochloride | Heparan Sulfate
相关库: Anti-Prostate Cancer Compound Library | Anti-Cancer Metabolism Compound Library | Anti-Cancer Compound Library | Neuronal Differentiation Compound Library | Bioactive Compounds Library Max | Anti-Ovarian Cancer Compound Library | Inhibitor Library | Cytoskeletal Signaling Pathway Compound Library | Anti-Colorectal Cancer Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途