化合物 3,4,5-Trihydroxycinnamic acid decyl ester T39189

Product Introduction
Bioactivity


英文名: 3,4,5-Trihydroxycinnamic acid decyl ester

描述: 3,4,5-Trihydroxycinnamic acid decyl ester, an effective inhibitor of lipid absorption and accumulation, exhibits anti-obesity properties. Additionally, this compound acts as a pancreatic lipase inhibitor, with an EC 50 of around 0.9 μM.

体外活性: 3,4,5-Trihydroxycinnamic acid decyl ester (30 μM) exhibits an inhibitory potency of approximately 92% for pancreatic lipase in vitro[1]. 3,4,5-Trihydroxycinnamic acid decyl ester (0.1-40 μM) inhibits pancreatic lipase activity in dose-dependent manner, with an EC 50 value being approximately 0.9 μM[1]. 3,4,5-Trihydroxycinnamic acid decyl ester inhibits pancreatic lipase in vitro and lipid accumulation during 3T3-L1 cell differentiation[1].

体内活性: 3,4,5-Trihydroxycinnamic acid decyl ester (30-150 mg/kg; p.o.) suppresses a rise in blood triglyceride (TG) levels in mice given corn oil orally[1]. Animal Model: 6 weeks old Male ddY mice[1]Dosage: 30 mg/kg, 150 mg/kg Administration: Oral administration Result: Reduced plasma TG in a dose-dependent manner.

存储条件: store at low temperaturePowder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: 3,4,5 Trihydroxycinnamic acid decyl ester | 3,4,5-Trihydroxycinnamic acid decyl ester | 3,4,5Trihydroxycinnamic acid decyl ester

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途