维迪西妥单抗 T39595

Product Introduction
Bioactivity


英文名: Disitamab vedotin

描述: Disitamab vedotin (RC-48) 是一种抗体-活性分子偶联物 (ADC)，包含抗人表皮生长因子受体2 (HER2) 的单克隆抗体，该单克隆抗体通过可降解连接子结合到细胞毒性剂 MMAE。Disitamab vedotin 在不同HER-2表达水平胃癌细胞中显示出抗肿瘤和抗增殖活性且抑制胃癌细胞中HER-2蛋白的表达。

体外活性: The antibody component was a humanized monoclonal antibody designed to target HER2, while the small molecule toxin utilized was monomethyl auristatin E (MMAE), a synthetic antineoplastic agent. A protease-cleavable linker was used to covalently attach MMAE to the antibody.[2]

存储条件: store at low temperature,keep away from direct sunlightstore at -20°C

关键字: Disitamab vedotin

相关产品: (E)-AG 99 | OK2 | AV-412 | (E/Z)-CP-724714 | Pelitinib | EAI045 | Poziotinib | WAY-270360 | CL-387785 | JCN037

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途