diABZI-C2-NH2 T39597

Product Introduction
Bioactivity


英文名: diABZI-C2-NH2

描述: DiABZI-C2-NH2, a STING agonist with a primary amine functionality, is an active analogue.

体外活性: The author developed a linking strategy to synergize the effect of two symmetry-related amidobenzimidazole (ABZI)-based compounds to create linked ABZIs (diABZIs) with enhanced binding to STING and cellular function. Intravenous administration of a diABZI STING agonist to immunocompetent mice with established syngeneic colon tumours elicited strong anti-tumour activity, with complete and lasting regression of tumors[1]. diABZI-C2-NH2 is covalently immobilized on sepharose beads and is used to affinity-capture potential target proteins from a THP1 cell lysate[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: diABZI-C-2-NH2 | diABZI C2 NH2 | diABZIC2NH2

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途