KRAS G12C inhibitor 18 T40285
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 2649788-45-2 | ¥39,200.00 | 询底价 |
Product Introduction
Bioactivity
英文名: KRAS G12C inhibitor 18
描述: KRAS G12C inhibitor 18 is a potent, orally active compound that inhibits KRAS G12C and exhibits anti-tumor activities.
体外活性: KRAS G12C inhibitor 18 (compound 34) inhibits the growth of many KRas G12C mutant tumor cell lines (such as H358, SW1436, MiaPaca-2 cells, etc.)[1].
体内活性: KRAS G12C inhibitor 18 exhibits a dose dependent inhibiton of pERK and active KRas after a single dose treatment from 12.5 to 100 mg/kg at 8 hours[1]. KRAS G12C inhibitor 18 (30 mg/kg; p.o.; twice daily) exhibits anti-tumor growth activity in lung cancer H358 xenograft mouse model[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: KRAS G-12C inhibitor 18 | KRAS G12C inhibitor 18
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途