化合物MST-312 T41290

Product Introduction
Bioactivity


英文名: MST-312

描述: MST-312 (Telomerase Inhibitor IX) 是绿茶表没食子儿茶素没食子酸酯 (EGCG) 的衍生物。MST-312 是 telomerase 抑制剂，可用于肿瘤的研究，如多发性骨髓瘤 (MM)。

体外活性: In U-266 cells, MST-312 (2 μM) upregulates the pro-apoptotic gene Bax and down-regulates the anti-apoptotic gene Bcl-2 and suppresses the expression of c-Myc and hTERT genes. MST-312 (2-8 μM) reduces cellular viability in a dose dependent and time-dependent manner. MST-312 (2-8 μM) induces cell apoptosis in a dose-dependent manner[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: H2O : Insoluble
DMSO : 70 mg/mL (184.04 mM)


关键字: EGCG | Telomerase | epigallocatechin | gallate | MST312 | Inhibitor | multiple | tea | MST 312 | MST-312 | derivative | cancer | inhibit | myeloma

相关产品: L-778123 hydrochloride | Telomerase-IN-2 | Cycloastragenol | TMPyP4 tosylate | Cyclogalegenin | RHPS4 | Braco-19 trihydrochloride | BIBR 1532 | Lipiferolide | Telomerase-IN-1

相关库: Anti-Cancer Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Anti-Cancer Active Compound Library | DNA Damage & Repair Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途