化合物F1063-0967 T4308

Product Introduction
Bioactivity


英文名: F1063-0967

描述: F1063-0967 是双特异性磷酸酶 26 抑制剂，其IC50=11.62 μM。

细胞实验: The IMR-32 cells are plated in 96-well plates with 1×103 cells per well. After the cells are allowed to settle for 24 h, F1063-0967 (0, 10, 1, and 0.1 μM) is added. An MTTassay is performed. For cell lines HL7702 and SH-SY5Y, the cells are allowed to settle for 24 h, F1063-0967 (10 μM) is added, then MTT assays are carried out after 72 h.

体外活性: 在浓度超过0.1μM时，F1063-0967显著诱导IMR32细胞发生凋亡。F1063-0967对IMR-32细胞线的凋亡诱导作用，其半抑制浓度（IC50）值为4.13μM。F1063-0967对HL7702细胞线无影响，并且对SH-SY5Y细胞线的抑制作用较小。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 60 mg/mL (123.82 mM)


关键字: Phosphatase | F10630967 | F1063-0967 | inhibit | Inhibitor | F-1063-0967 | F1063 0967

相关产品: KLH45 | PP5-IN-1 | Etidronic acid | DA-3003-1 | Methyl orsellinate | Tartaric acid disodium dihydrate | BTdCPU | D-ERYTHRO-SPHINGOSINE | 3α-Aminocholestane | TPI-1

相关库: Glycometabolism Compound Library | Anti-Metabolism Disease Compound Library | Bioactive Compounds Library Max | Phosphatase Inhibitor Library | Inhibitor Library | Lipid Metabolism Compound Library | Metabolism Compound Library | Covalent Inhibitor Library | Bioactive Compound Library

化合物F1063-0967 T4308信息由TargetMol中国为您提供，如您想了解更多关于化合物F1063-0967 T4308报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途