化合物AG 555 T4326

Product Introduction
Bioactivity


英文名: AG 555

描述: AG 555 (Tyrphostin B46)是一种选择性EGFR 的有效抑制剂，可阻断Cdk2活化。它是一种抗逆转录病毒药。

体外活性: Cell incubation in the presence of 30 μM AG 555 results in a selective down-regulation of the most abundant viral transcripts already 4 h after drug application. AG55 inhibits the growth of HPV16-immortalized cells. AG555 is already effective at 10 μM (IC50=6.4, respectively), and the cells remain arrested after withdrawal of the compound on day 5 as monitored on days 8 and 12.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 9.7 mg/mL(30 mM)


关键字: EGFR | AG-555 | Reverse Transcriptase | Bovine | HER1 | BPV | ErbB-1 | Inhibitor | Epidermal growth factor receptor | AG 555 | Tyrphostin AG-555 | AG555 | inhibit | Tyrphostin AG555 | antiretroviral | Papillomavirus

相关产品: Neolinine | Allitinib | Lazertinib | BLU-945 | AEE788 | JH-XI-10-02 | EGFR-IN-82 | Icotinib Hydrochloride | Lapatinib ditosylate monohydrate | Petosemtamab

相关库: Anti-Liver Cancer Compound Library | Cytokine Inhibitor Library | Angiogenesis related Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Kinase Inhibitor Library | Anti-Colorectal Cancer Compound Library | Tyrosine Kinase Inhibitor Library | Anti-Infection Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途