化合物ALW-II-41-27 T4344

Product Introduction
Bioactivity


英文名: ALW-II-41-27

描述: ALW-II-41-27 (Eph receptor tyrosine kinase inhibitor) 是一种 Eph 受体酪氨酸激酶抑制剂，可用于治疗癌症。

体外活性: ALW-II-41-27 inhibits Ba/F3 cells (EC50<500 nM) transformed with Tel fusions of Kit, EphA3, Fms, KDR, FLT1, FGR, Src, Bmx, Lyn, and Bcr-Abl. ALW-II-41-27 has cross-reactivity with Bcr-Abl. ALW-II-41-27 inhibits b-Raf, CSF1R, DDR1, DDR2, EphA2, EphA8, EphB1, EphB2, Kit, EphB3, Frk, Lck, EphA5, p38α, p38β, PDGFRβ, PDGFRα, and Raf1.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 55 mg/mL (90.51 mM)


关键字: ALWII4127 | Inhibitor | inhibit | Ephrin Receptor | ALW-II-41-27 | ALW II 41 27

相关产品: UniPR1449 | Dasatinib monohydrate | AWL-II-38.3 | Tesevatinib | 123C4 | Tivozanib | KYL acetate(676657-00-4 free base) | Ehp-inhibitor-2 | Eph inhibitor 2 | NVP-BHG712 isomer

相关库: Anti-Cancer Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Neural Regeneration Compound Library | Inhibitor Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Anti-Cancer Active Compound Library | Target-Focused Phenotypic Screening Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途