化合物4-IBP T4596
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
200 mg | 155798-08-6 | ¥4,980.00 | 询底价 |
25 mg | 155798-08-6 | ¥1,350.00 | 询底价 |
5 mg | 155798-08-6 | ¥455.00 | 询底价 |
2 mg | 155798-08-6 | ¥283.00 | 询底价 |
1 mL | 155798-08-6 | ¥490.00 | 询底价 |
100 mg | 155798-08-6 | ¥3,490.00 | 询底价 |
10 mg | 155798-08-6 | ¥728.00 | 询底价 |
50 mg | 155798-08-6 | ¥2,320.00 | 询底价 |
Product Introduction
Bioactivity
英文名: 4-IBP
描述: 4-IBP 是一种选择性σ1 激动剂,对σ1 受体的亲和力高,Ki 值为1.7 nM;对 σ2 受体的亲和力稍弱,Ki 值为 25.2 nM。
体外活性: 4-IBP is a σ1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells. 4-IBP is used to investigate whether targeting theσ1 receptor could modify in vitro the migration rates of human cancer cells and increase the sensitivity of metastasizing human A549 NSCLC cells and infiltrating human glioblastoma cells to cytotoxic insults of either proapoptotic or proautophagic drugs.[1]
体内活性: 4-IBP increases the antitumor effects of temozolomide and irinotecan in immunodeficient mice that were orthotopically grafted with invasive cancer cells.[1]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 7.86 mg/mL (18.69 mM)
Ethanol : 5 mM
关键字: 4IBP | Inhibitor | Sigma Receptor | 4-IBP | inhibit | 4 IBP
相关产品: AB21 oxalate | S1R agonist 1 hydrochloride | 4-PPBP maleate | BMY-14802 hydrochloride | EST64454 hydrochloride | Blonanserin | Sigma-1 receptor antagonist 1 | SARS-CoV-2-IN-57 | Glycerol phenylbutyrate | BD-1047 dihydrobromide
相关库: Anti-Cancer Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | GPCR Compound Library | Target-Focused Phenotypic Screening Library | NO PAINS Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途