坎格雷洛四钠盐 T5036
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mg | 163706-36-3 | ¥328.00 | 询底价 |
10 mg | 163706-36-3 | ¥1,290.00 | 询底价 |
2 mg | 163706-36-3 | ¥478.00 | 询底价 |
100 mg | 163706-36-3 | ¥5,390.00 | 询底价 |
1 mL | 163706-36-3 | ¥1,230.00 | 询底价 |
25 mg | 163706-36-3 | ¥2,350.00 | 询底价 |
5 mg | 163706-36-3 | ¥828.00 | 询底价 |
50 mg | 163706-36-3 | ¥3,780.00 | 询底价 |
500 mg | 163706-36-3 | ¥10,900.00 | 询底价 |
Product Introduction
Bioactivity
英文名: cangrelor tetrasodium
描述: Cangrelor tetrasodium 是三磷酸腺苷类似物,是可逆的选择性血小板P2Y12拮抗剂,也是非特异性的GPR17拮抗剂。它直接阻断腺苷二磷酸诱导的血小板活化和聚集,具有迅速有效的抗血小板作用。
体外活性: cangrelor, a non-sepesific GPR17 antagonist, alleviates pulmonary fibrosis partly by inhibiting macrophage inflammation in mice.Cangrelor is also a well-known anti-platelet agent. cangrelor (10 mg/kg) not only significantly decreased BLM-induced release of inflammatory cytokines (PF4, CD40 L and MPO), but also decreased the increment of platelets, neutrophils and platelet-neutrophil aggregates in the fibrotic lung and in the peripheral blood of BLM-treated mice. In addition, cangrelor decreased the number of CD40 and MPO double positive neutrophils and the expression level of CD40 in BLM-treated mouse lungs[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 8.65 mg/mL (10 mM)
关键字: aggregation | cangrelor tetrasodium | fibrosis | P2Y Receptor | pulmonary | platelet | Inhibitor | inflammation | intravenous | cangrelor | antiplatelet | inhibit
相关产品: Clopidogrel hydrogen sulfate | 1-[(5-methylisoxazol-3-yl)methyl]piperazine | AZD1283 | Diquafosol tetrasodium | Clopidogrel | Uridine 5′-diphosphoglucose disodium salt | NF546 hydrate | PPTN | Ticagrelor | PPTN hydrochloride
相关库: FDA-Approved Drug Library | Drug Repurposing Compound Library | Anti-Cancer Compound Library | Anti-Cancer Drug Library | Membrane Protein-targeted Compound Library | GPCR Compound Library | Anti-Cancer Clinical Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | EMA Approved Drug Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途