化合物Gap 26 T5192

Product Introduction
Bioactivity


英文名: Gap 26

描述: Gap 26 是模拟肽，对应于连接蛋白 43 的残基 63-75，是间隙连接阻断剂。

体外活性: Oscillatory behaviour was abolished by Gap 26 at concentrations of 100-300 microM (IC50 of 20-30 microM), without a change in average tone. No synergy was evident between peptides corresponding to the extracellular loops, and cytoplasmic loop peptides were biologically inactive [1]. Photoliberating InsP(3) in a single cell within a confluent culture triggered an intercellular calcium wave, which was inhibited by the connexin mimetic peptide gap 26 [2].

存储条件: keep away from moisturePowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 10 mM


关键字: Inhibitor | Gap26 | Gap-26 | Gap 26 | Gap Junction Protein | inhibit

相关产品: Meclofenamic acid | Peptide5 TFA | Carbenoxolone disodium | Rotigaptide TFA(355151-12-1 free base) | Larazotide acetate | Danegaptide Hydrochloride | TAT-Gap19 acetate | Gap 27 | Gap19 | Meclofenamic acid sodium

相关库: Peptide Compound Library | Cytoskeletal Signaling Pathway Compound Library | Target-Focused Phenotypic Screening Library | NO PAINS Compound Library

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